Selected Publications
Tao Yin#, Guoping Wang#, Liuyang Wang, Poorva Mudgal, Ergang Wang, Christopher C. Pan, Peter B. Alexander, Haiyang Wu, Chengjie Cao, Yaosi Liang, Lianmei Tan, De Huang, Mengyang Chong, Rui Chen, Bryan Jian Wei Lim, Kun Xiang, Wei Xue, Lixin Wan, Hailan Hu, Yuin-Han Loh, Xiao-Fan Wang*, Qi-Jing Li*. Breaking NGF-TrkA immunosuppression in melanoma sensitizes immunotherapy for durable memory T cell protection. Nature Immunology 2024;25(2):268-281.
Lianmei Tan#, Tao Yin#, Handan Xiang#, Liuyang Wang, Poorva Mudgal, Junying Chen, Yi Ding, Guoping Wang, Bryan Jian Wei Lim, Yuqi Huang, De Huang, Yaosi Liang, Peter B. Alexander, Kun Xiang, Ergang Wang, Chengsong Yan, Zhehao Ma, Minjia Tan, Qi-Jing Li, Xiao-Fan Wang. Aberrant cytoplasmic expression of UHRF1 restrains the MHC-I-mediated anti-tumor immune response. Nature Communications 2024;15(1):8569.
Tao Yin#,*. Improving T cell therapy: in vivo CRISPR-Cas9 screens tell us how to do. Precision Clinical Medicine 2021;4(3):176-178.
Mengyang Chong#, Tao Yin#, Rui Chen, Han-Dan Xiang, Li-Feng Yuan, Yi Ding, Christopher C Pan, Zhen Tang, Peter B Alexander, Qi-Jing Li*, Xiao-Fan Wang*. CD36 initiates the secretory phenotype during the establishment of cellular senescence. EMBO Reports 2018;19(6). pii: e45274. doi: 10.15252/embr.201745274.
Tao Yin#, Guoping Wang#, Sisi He, Guobo Shen, Chao Su, Yan Zhang, Xiawei Wei, Tinghong Ye, Ling Li, Shengyong Yang, Dan Li, Fuchun Guo, Zeming Mo, Yang Wan, Ping Ai, Xiaojuan Zhou, Yantong Liu, Yongsheng Wang*, Yuquan Wei. Malignant pleural effusion and ascites induce epithelial-mesenchymal transition and cancer stem-like cell properties via the vascular endothelial growth factor (VEGF)/phosphatidylinositol 3-Kinase (PI3K)/Akt/mechanistic target of rapamycin (mTOR) pathway. Journal of Biological Chemistry 2016; 291(52): 26750–26761.
Tao Yin#, Guoping Wang#, Tinghong Ye*,Yongsheng Wang*. Sulindac, a non-steroidal anti-inflammatory drug, mediates breast cancer inhibition as an immune modulator. Scientific Reports2016; 6: 19534.
Tao Yin#,*, Guoping Wang, Sisi He, Qin Liu, Jianhong Sun, Yongsheng Wang*. Human breast cancer stem cells exhibit enhanced sensitivity to IL-2 and IL-15 activated natural killer cells cytotoxicity. Cellular Immunology2016; 300:41-45.
Tao Yin#, Sisi He#, Xiaoling Liu#, Wei Jiang, Tinghong Ye, Ziqiang Lin, Yaxiong Sang, Chao Su, Yang Wan, Guobo Shen, Xuelei Ma, Min Yu, Fuchun Guo, Yanyang Liu, Ling Li, Qiancheng Hu, Yongsheng Wang, Yuquan Wei. Extravascular red blood cells and hemoglobin promote tumor growth and therapeutic resistance as endogenous danger signals.The Journal of Immunology2015; 194:429-437.
Tao Yin#, Sisi He#, Chao Su, Xiancheng Chen, Dongmei Zhang, Yang Wan, Tinghong Ye, Guobo Shen, Yongsheng Wang, Huashan Shi, Li Yang*, Yuquan Wei*. Genetically modified human placenta-derived mesenchymal stem cells with FGF-2 and PDGF-BB enhance neovascularization in a model of hindlimb ischemia. Molecular Medicine Reports 2015; 12(4): 5093-5099.
Tao Yin#, Sisi He, Tinghong Ye, et al. Antiangiogenic therapy using sunitinib combined with rapamycin retards tumor growth but promotes metastasis. Translational Oncology 2014; 7(2): 221-229.
Sisi He#, Tao Yin#, Dan Li, Xiang Gao, Yang Wan, Xuelei Ma, Tinghong Ye, Fuchun Guo, Jianhong Sun, Ziqiang Lin, Yongsheng Wang*. Enhanced interaction between natural killer cells and lung cancer cells: involvement in gefitinib-mediated immunoregulation.Journal of Translational Medicine 2013, 11:186.
Xiaoshuang Jiang#, Zhixing Chen#, Guobo Shen, Yong Jiang, Liangjun Wu, Xue Li, Guoping Wang*, Tao Yin*. Psychotropic agent thioridazine elicits potent in vitro and in vivo anti-melanoma effects. Biomedicine&Pharmacotherapy 2018; 97: 833-837.
Guoping Wang#, Guobo Shen, Tao Yin*. In vitro effect of deferoxamine on mesenchymal stromal cells from tumor and bone marrow. Environmental Toxicology and Pharmacology 2017; 49: 58-64.